0. Either Sudo or login as root on the machine
cd /tmp
wget http://apt.sw.be/redhat/el5/en/i386/rpmforge/RPMS/rpmforge-release-0.3.6-1.el5.rf.i386.rpm
wget http://apt.sw.be/redhat/el5/en/i386/rpmforge/RPMS/rpmforge-release-0.3.6-1.el5.rf.i386.rpm
rpm -Uvh rpmforge-release-0.3.6-1.el5.rf.i386.rpm
3. Install wine
yum install wine -y enablerepo=rpmforge
4. Launch Wine from the Centos Applications menu
-n